The Araripe Basin in NE Brazil was originally formed during Cretaceous times, as South America and Africa broke up. The basin is an important analogue to offshore South Atlantic break-up basins; its sediments were uplifted and are now found at 1000 m height, allowing for studies thereof, but the cause of the uplift remains debated. Here we ran a series of tectonic laboratory experiments that show how a specific plate tectonic configuration can explain the evolution of the Araripe Basin.