We present a workflow that models the impact of stress regime change on the permeability of fractured Latemar carbonate buildup using a displacement-based linear elastic finite-element method (FEM) and outcrop data. Stress-dependent heterogeneous apertures and effective permeability were calculated and constrained by the study area's stress directions. Simulated far-field stresses at NW–SE subsidence deformation and N–S Alpine deformation increased the overall fracture aperture and permeability.