Understanding the flow of large ice masses on Earth is a major challenge in our changing climate. Deformation mechanisms are governed by the strong anisotropy of ice. As anisotropy is currently moving into the focus of ice sheet flow studies, we provide a detailed analysis of microstructure data from natural ice core samples which directly relate to anisotropic plasticity. Our findings reveal surprising dislocation activity which seems to contradict the concept of macroscopic ice anisotropy.