New satellite geodetic data (PS-InSAR) evidence a generalized subsidence and an eastward tilting of southeastern Sicily combined with a local relative uplift along its eastern coast. We perform flexural and elastic modeling and show that the slab pull force induced by the Ionian slab roll-back and extrado deformation reproduce the measured surface deformation. Finally, we propose an original seismic cycle model that is mainly driven by the southward migration of the Ionian slab roll-back.